基于静息态脑电微状态对成人注意缺陷多动障碍的判别Discrimination of adult with attention deficit/hyperactivity disorder based on EEG microstate
陈彦博;王长明;李卉;赵琦华;罗翔升;吴占良;曹庆久;孙黎;王玉凤;
摘要(Abstract):
目的:探究注意缺陷多动障碍(ADHD)患者的静息态脑电微状态特征及其对成人ADHD的判别能力。方法:收集36例符合DSM-IV标准的成人ADHD患者和46例正常对照的静息态脑电数据,比较两组脑电微状态的时间覆盖率和优势切换方向。运用Fisher线性判别,探讨脑电微状态对ADHD的判别能力。结果:两组均呈现5种脑电微状态(A~E),ADHD组微状态C时间覆盖率低于对照组[(16.6±4.3)%vs.(23.6±6.6)%,P<0.001],微状态D时间覆盖率高于对照组[(21.6±4.1)%vs.(15.1±5.9)%,P<0.001]。微状态AB、AD、BC、BE、CD、DE之间的优势切换方向的组间差异有统计学意义(均P<0.05)。用时间覆盖率参数作判别准确率84.2%,优势切换方向参数作判别准确率91.5%。结论:用脑电微状态参数对ADHD相对于正常对照作判别有较高的正确率,值得进一步探讨临床应用前景。
关键词(KeyWords): 注意缺陷多动障碍;脑电微状态;判别分析
基金项目(Foundation): 国家自然科学基金(81771479、81971284);; 北京市科技计划项目(Z171100001017089);; 首都卫生发展科研专项项目(2020-1-4111)
作者(Author): 陈彦博;王长明;李卉;赵琦华;罗翔升;吴占良;曹庆久;孙黎;王玉凤;
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