陈彦博;王长明;李卉;赵琦华;罗翔升;吴占良;曹庆久;孙黎;王玉凤;

• 1:北京大学第六医院北京大学精神卫生研究所国家卫生健康委员会精神卫生学重点实验室(北京大学)国家精神心理疾病临床医学研究中心(北京大学第六医院)
• 2:首都医科大学附属北京宣武医院

摘要(Abstract)：

目的:探究注意缺陷多动障碍(ADHD)患者的静息态脑电微状态特征及其对成人ADHD的判别能力。方法:收集36例符合DSM-IV标准的成人ADHD患者和46例正常对照的静息态脑电数据,比较两组脑电微状态的时间覆盖率和优势切换方向。运用Fisher线性判别,探讨脑电微状态对ADHD的判别能力。结果:两组均呈现5种脑电微状态(A～E),ADHD组微状态C时间覆盖率低于对照组[(16.6±4.3)%vs.(23.6±6.6)%,P<0.001],微状态D时间覆盖率高于对照组[(21.6±4.1)%vs.(15.1±5.9)%,P<0.001]。微状态AB、AD、BC、BE、CD、DE之间的优势切换方向的组间差异有统计学意义(均P<0.05)。用时间覆盖率参数作判别准确率84.2%,优势切换方向参数作判别准确率91.5%。结论:用脑电微状态参数对ADHD相对于正常对照作判别有较高的正确率,值得进一步探讨临床应用前景。

关键词(KeyWords)： 注意缺陷多动障碍;脑电微状态;判别分析

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(81771479、81971284);; 北京市科技计划项目(Z171100001017089);; 首都卫生发展科研专项项目(2020-1-4111)

作者(Author): 陈彦博;王长明;李卉;赵琦华;罗翔升;吴占良;曹庆久;孙黎;王玉凤;

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