刘勤一;李雪;王慧;曹庆久;刘靖;

• 1:北京大学第六医院北京大学精神卫生研究所国家卫生健康委员会精神卫生学重点实验室(北京大学)国家精神心理疾病临床医学研究中心(北京大学第六医院)

摘要(Abstract)：

目的:了解神经性厌食少年的神经系统软体征特点及其相关因素。方法:入组符合ICD-10神经性厌食诊断标准的少年32例及性别、年龄相匹配的正常对照32例,使用剑桥神经科检查(CNI)软体征测试分量表对两组被试进行神经系统软体征检查和评分。结果:神经性厌食组CNI软体征测试分量表中有9项的异常发生率均高于正常对照组(均P<0.05),软体征测试分量表分[5.0(1.0,20.0)vs.2.0(0.0,8.0)]及运动协调[3.5(0.0,15.0)vs.1.0(0.0,8.0)]、感觉统合[2.0(0.0,8.0)vs.0.5(0.0,5.0)]2个因子分均高于正常对照组(均P<0.05)。神经性厌食组软体征测试分量表分及运动协调、感觉统合因子分与年龄、性别、病程、体质量指数(BMI)及共病抑郁相关性均无统计学意义(r=-0.22～0.29,均P>0.05)。结论:神经性厌食少年可能存在神经系统软体征异常,且异常严重程度与年龄、性别、病程、体质量指数及共病抑郁无明显相关性。

关键词(KeyWords)： 少年;神经性厌食;神经系统软体征;相关因素;横断面研究

Abstract:

Keywords:

基金项目(Foundation): 国家科技支撑计划(2009BA177B02);; 国家自然科学基金(81471382)

作者(Authors): 刘勤一;李雪;王慧;曹庆久;刘靖;

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